101070950 Exploting ex vivo expansion and deep multiomics profiling to bring novel, efficient and safer hematopoietic stem cell gene therapies to clinical application (X-PAND)
The technological breakthrough of this proposal is to capture HSC in the ex vivo culture, achieved by a combination of innovative expansion conditions, iterative cell sorting and multiomics single cell profiling. Rapid, quantitative and qualitative in vitro HSC assessment predictive of in vivo function may become a sustainable alternative to mouse xenotransplantation experiments.
![XPAND](/sites/default/files/styles/cabecera_1920x900/public/imagenes/proyectos/cellule1-scaled.jpg?itok=dd16VeU3)
![](/sites/default/files/imagenes/logotipos/ec_european_commission-web_1.jpg)
![XPAND](/sites/default/files/imagenes/logotipos/xpand-300x102.jpg)