X-PAND: Exploting ex vivo expansion and deep multiomics profiling to bring novel, efficient and safer hematopoietic stem cell gene therapies to clinical application

X-PAND

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Ikerketa proiektuak

Proiektu lehiakorrak

Nazioarteko proiektuak

Proiektuen kudeaketa unitatea

proyectos.nb@navarra.es

/eu/investigacion/proyectos

X-PAND: Exploting ex vivo expansion and deep multiomics profiling to bring novel, efficient and safer hematopoietic stem cell gene therapies to clinical application

The technological breakthrough of this proposal is to capture HSC in the ex vivo culture, achieved by a combination of innovative expansion conditions, iterative cell sorting and multiomics single cell profiling. Rapid, quantitative and qualitative in vitro HSC assessment predictive of in vivo function may become a sustainable alternative to mouse xenotransplantation experiments.

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X-PAND website

Finantza-erakundea

https://eismea.ec.europa.eu/index_en