101070950 Exploting ex vivo expansion and deep multiomics profiling to bring novel, efficient and safer hematopoietic stem cell gene therapies to clinical application (X-PAND)

X-PAND

Ikerketa

Ikerketa proiektuak

Proiektu lehiakorrak

Nazioarteko proiektuak

Proiektuen kudeaketa unitatea

proyectos.nb@navarra.es

/eu/investigacion/proyectos

101070950 Exploting ex vivo expansion and deep multiomics profiling to bring novel, efficient and safer hematopoietic stem cell gene therapies to clinical application (X-PAND)

The technological breakthrough of this proposal is to capture HSC in the ex vivo culture, achieved by a combination of innovative expansion conditions, iterative cell sorting and multiomics single cell profiling. Rapid, quantitative and qualitative in vitro HSC assessment predictive of in vivo function may become a sustainable alternative to mouse xenotransplantation experiments.

Web

X-PAND website

Finantza-erakundea

https://eismea.ec.europa.eu/index_en